2,4,6-Tribromophenol

CAS NO.：118-79-6
Empirical Formula: C6H3Br3O
Molecular Weight: 330.8
MDL number: MFCD00002150
EINECS: 204-278-6
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-04 14:24:59

What is 2,4,6-Tribromophenol?

Chemical properties

2,4,6-Tribromophenol is a white needle-shaped into prismatic crystals with has a penetrating bromine odor. In alcohol, chloroform, ether and caustic alkali solution, almost insoluble in water, sweet taste.

The Uses of 2,4,6-Tribromophenol

2,4,6-Tribromophenol is used as a certified reference standard for the determination of the analyte in multiple solid formulation drug products using gas chromatography coupled to tandem mass spectrometry.

The Uses of 2,4,6-Tribromophenol

2,4,6-Tribromophenol was used in analysis of nonylphenol, nonylphenol monoethoxylate and octylphenol in sediment, water and fish tissue.

What are the applications of Application

2,4,6-Tribromophenol is halogenated phenol that undergoes oxidative degradation

Definition

ChEBI: 2,4,6-tribromophenol is a bromophenol that is phenol in which the hydrogens at positions 2, 4 and 6 have been replaced by bromines. It is commonly used as a fungicide and in the preparation of flame retardants. It has a role as an environmental contaminant, a fungicide and a marine metabolite.

Production Methods

2,4,6-Tribromophenol is produced by the controlled bromination of phenol.

General Description

Soft, long, white crystals with a bromine odor.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

2,4,6-Tribromophenol can react with oxidizing materials .

Hazard

By ingestion, inhalation, skin absorption. Strong skin irritant.

Fire Hazard

Data is not available for 2,4,6-Tribromophenol. 2,4,6-Tribromophenol is probably non-flammable.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise the phenol from EtOH or pet ether. Dry it under vacuum over P2O5 at room temperature. [Beilstein 6 IV 1067.]

Properties of 2,4,6-Tribromophenol

Melting point:	90-94 °C(lit.)
Boiling point:	282-290 °C746 mm Hg(lit.)
Density	2.55
vapor density	11.4 (vs air)
vapor pressure	0.042-0.063Pa at 25℃
refractive index	1.5580 (estimate)
Flash point:	282-290°C subl.
storage temp.	2-8°C
solubility	water: soluble0.007g/100ml at 25°C
form	Powder
pka	6.34±0.23(Predicted)
color	White to slightly brown
Water Solubility	71 mg/L (15 ºC)
Merck	14,9613
BRN	776920
CAS DataBase Reference	118-79-6(CAS DataBase Reference)
NIST Chemistry Reference	Phenol, 2,4,6-tribromo-(118-79-6)
EPA Substance Registry System	2,4,6-Tribromophenol (118-79-6)

Safety information for 2,4,6-Tribromophenol

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H400:Hazardous to the aquatic environment, acute hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.