2,4,6-tribromophenol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2,4,6-tribromophenol
- CAS： 118-79-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Skin sensitization, Category 1
Eye irritation, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H317 May cause an allergic skin reaction
H319 Causes serious eye irritation
H400 Very toxic to aquatic life
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2,4,6-tribromophenol
- Common names and synonyms: 2,4,6-tribromophenol
- CAS number: 118-79-6
- EC number: 204-278-6
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Most important symptoms/effects, acute and delayed
SYMPTOMS: This chemical may cause severe irritation to the skin, eyes, and mucous membranes. ACUTE/CHRONIC HAZARDS: This chemical and its decomposition products are considered to be very toxic by: ingestion, inhalation and skin absorption. It emits toxic fumes. It may react violently with oxidizing materials. It is also known to be a strong skin irritant. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
SECTION 5: Firefighting measures
Suitable extinguishing media
Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Specific hazards arising from the chemical
Data is not available for this compound. It is probably non-flammable. (NTP, 1992)
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers.
Methods and materials for containment and cleaning up
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep tightly closed.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Avoid inhalation of dust.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Solid.
-
Colour：
White to off white.
-
Odour：
Penetrating bromine odor
-
Melting point/freezing point：
94.35°C. Remarks:Melting point.
-
Boiling point or initial boiling point and boiling range：
244 °C. Remarks:Unknown whether boiling point is given for standard and pressure.
-
Flammability：
Not combustible.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
98°C(lit.)
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Slightly soluble (1-10 mg/ml) (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Pow = 3.7. Temperature:23.5 °C.;Pow = 4 600. Temperature:23.5 °C.
-
Vapour pressure：
0.063 Pa. Temperature:25 °C.
-
Density and/or relative density：
2.618. Temperature:20 °C.
-
Relative vapour density：
11.4 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Slightly soluble in water.
Chemical stability
no data available
Possibility of hazardous reactions
2,4,6-TRIBROMOPHENOL can react with oxidizing materials (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Hydrogen bromide gas.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 1,486 mg/kg bw.
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes.
STOT-repeated exposure
Repeated or prolonged contact may cause skin sensitization.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: EC50 - Cyprinus carpio - 1.1 - 1.8 mg/L - 24.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 0.26 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 0.4 mg/L - 72 h.
- Toxicity to microorganisms: activated sludge, domestic and industrial, seeded with sediment exposed to brominated organics.
Persistence and degradability
AEROBIC: 2,4,6-Tribromophenol, present at 100 mg/L, reached 49% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). 2,4,6-Tribromophenol was not degraded over 14 days in a marine sediment slurry, prepared from sediment from the 0 to 1 cm interval with equivalent amounts of filtered seawater(2). No ring degradation was reported for 2,4,6-tribromophenol, at 100 mg/L, over a 5-day period using a soil inoculum(3). Water samples collected from two treatment ponds were unable to degrade 2,4,6-tribromophenol over 32 days(4).
Bioaccumulative potential
BCF values of 513(1,3) and 83(2) were measured in Brachydanio rerio and fathead minnow, respectively, for 2,4,6-tribromophenol. According to a classification scheme(4), these BCF values suggest the potential for bioconcentration in aquatic organisms is moderate to high.
Mobility in soil
The Koc of 2,4,6-tribromophenol is estimated as 4,200(SRC), using a log Kow of 4.13(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2,4,6-tribromophenol is expected to have slight mobility in soil. The pKa of 2,4,6-tribromophenol is 6.80(4), indicating that this compound will partially exist in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.