2,4,6-Tribromoaniline

CAS NO.：147-82-0
Empirical Formula: C6H4Br3N
Molecular Weight: 329.81
MDL number: MFCD00007634
EINECS: 205-700-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 03:14:43

What is 2,4,6-Tribromoaniline?

Chemical properties

BEIGE TO GREY CRYSTALLINE SOLID

The Uses of 2,4,6-Tribromoaniline

2,4,6-Tribromoaniline was used in simultaneous determination of phenolic brominated flame retardants and their by-products in water.

The Uses of 2,4,6-Tribromoaniline

A trihalogen substituted aniline with potential inhibitory effect on human cytochrome P 450 (CYP) 2E1.

Preparation

2,4,6-Tribromoaniline can be prepared by treating bromine water with aniline in a solution of acetic acid or dilute hydrochloric acid:
synthesis of 2,4,6-Tribromoaniline
synthesis-of-2-4-6-tribromoaniline-from-aniline

General Description

Electrochemical oxidation of 2,4,6-tribromoaniline in aqueous sulphuric acid solutions at platinum electrode has been studied by rotating disc electrode and cyclic voltammetry. 2,4,6-Tribromoaniline on closed-tube pyrolysis yields polybromophenazines. It is an intermediate in the formulation of flame retardants incorporated to plastic materials.

Purification Methods

Crystallise the aniline from MeOH. The benzenesulfonamide derivative has m 198o. [Beilstein 12 H 663, 12 I 329, 12 II 358, 12 III 1477, 12 IV 1538.]

Properties of 2,4,6-Tribromoaniline

Melting point:	120-122 °C(lit.)
Boiling point:	300 °C(lit.)
Density	2.35
refractive index	1.6890 (estimate)
Flash point:	300°C
solubility	alcohol: soluble (cold)(lit.)
form	powder to crystal
pka	-0.23±0.10(Predicted)
color	White to Almost white
Merck	14,9610
BRN	2209258
CAS DataBase Reference	147-82-0(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 2,4,6-tribromo-(147-82-0)
EPA Substance Registry System	2,4,6-Tribromoaniline (147-82-0)

Safety information for 2,4,6-Tribromoaniline

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08
GHS Hazard Statements	H301:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.