2,4-Dimethoxyaniline
- CAS NO.：2735-04-8
- Empirical Formula: C8H11NO2
- Molecular Weight: 153.18
- MDL number: MFCD00008371
- EINECS: 220-355-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:18:12
What is 2,4-Dimethoxyaniline?
Chemical properties
black crystals
The Uses of 2,4-Dimethoxyaniline
Various 2,4-dimethoxyphenylsemicarbazones were synthesized starting from 2,4-dimethoxyaniline via a phenylcarbamate intermediate. The hydrochloride of 2,4-dimethoxyaniline was prepared by intro- ducing hydrogen chloride gas into an etheral solution and washing the precipitate with absolute diethyl ether.
Synthesis Reference(s)
Tetrahedron Letters, 34, p. 2441, 1993 DOI: 10.1016/S0040-4039(00)60436-7
General Description
Black crystalline solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2,4-Dimethoxyaniline neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: 2,4-Dimethoxyaniline is a local irritant.
Properties of 2,4-Dimethoxyaniline
| Melting point: | 33-36 °C (lit.) |
| Boiling point: | 75-80 C |
| Density | 1.075 g/mL at 25 °C (lit.) |
| refractive index | 1.4640 (estimate) |
| Flash point: | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | Crystalline Solid |
| pka | 5.14±0.10(Predicted) |
| color | Dark brown |
| Water Solubility | 7 g/L (20 ºC) |
| BRN | 638704 |
| Stability: | Stability Stable, but sensitive to prolonged exposure to light. Incompatible with acids. |
| CAS DataBase Reference | 2735-04-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenamine, 2,4-dimethoxy-(2735-04-8) |
| EPA Substance Registry System | 2,4-Dimethoxyaniline (2735-04-8) |
Safety information for 2,4-Dimethoxyaniline
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,4-Dimethoxyaniline
2,4-Dimethoxyaniline manufacturer
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