2,4-Dihydroxypyrimidine-5-carboxylic acid
Synonym(s):Isoorotic acid;Uracil-5-carboxylic acid
- CAS NO.：23945-44-0
- Empirical Formula: C5H4N2O4
- Molecular Weight: 156.1
- MDL number: MFCD00006023
- EINECS: 245-947-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:45:10
What is 2,4-Dihydroxypyrimidine-5-carboxylic acid?
Chemical properties
white to slightly yellow crystalline powder or
The Uses of 2,4-Dihydroxypyrimidine-5-carboxylic acid
2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.
What are the applications of Application
2,4-Dihydroxypyrimidine-5-carboxylic acid is has been used for the visual sensing of melamine
Definition
ChEBI: Uracil-5-carboxylic acid is a pyrimidinemonocarboxylic acid that is uracil carrying a carboxy group at position 5. It is functionally related to a uracil. It is a conjugate acid of a uracil-5-carboxylate. It is a tautomer of a 2,4-dihydroxypyrimidine-5-carboxylic acid.
General Description
2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.
Properties of 2,4-Dihydroxypyrimidine-5-carboxylic acid
| Melting point: | 283 °C (dec.)(lit.) |
| Boiling point: | 280.29°C (rough estimate) |
| Density | 1.6814 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in DMSO |
| pka | 5.08±0.20(Predicted) |
| form | Crystalline Powder |
| color | White to slightly yellow |
| Water Solubility | 1.8g/L(20 ºC) |
| CAS DataBase Reference | 23945-44-0(CAS DataBase Reference) |
| EPA Substance Registry System | 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo- (23945-44-0) |
Safety information for 2,4-Dihydroxypyrimidine-5-carboxylic acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2,4-Dihydroxypyrimidine-5-carboxylic acid
2,4-Dihydroxypyrimidine-5-carboxylic acid manufacturer
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