2,4-Difluoroaniline
- CAS NO.：367-25-9
- Empirical Formula: C6H5F2N
- Molecular Weight: 129.11
- MDL number: MFCD00007648
- EINECS: 206-687-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:16
What is 2,4-Difluoroaniline?
Chemical properties
dark red liquid
The Uses of 2,4-Difluoroaniline
2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.
General Description
Dark reddish-purple liquid.
Air & Water Reactions
2,4-Difluoroaniline may be sensitive to prolonged exposure to air. . Water soluble.
Reactivity Profile
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: 2,4-Difluoroaniline may be irritating to tissues.
Fire Hazard
2,4-Difluoroaniline is combustible.
Properties of 2,4-Difluoroaniline
| Melting point: | -7.5 °C (lit.) |
| Boiling point: | 170 °C/753 mmHg (lit.) |
| Density | 1.268 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 145 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | Not miscible or difficult to mix. |
| form | Liquid |
| pka | 3.26±0.10(Predicted) |
| Specific Gravity | 1.284 (20/4℃) |
| color | Clear brown |
| Water Solubility | 1-5 g/100 mL at 20.55 ºC |
| Merck | 14,3147 |
| BRN | 2802556 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. |
| CAS DataBase Reference | 367-25-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,4-Difluoroaniline(367-25-9) |
| EPA Substance Registry System | 2,4-Difluoroaniline (367-25-9) |
Safety information for 2,4-Difluoroaniline
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H311:Acute toxicity,dermal |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. |
Computed Descriptors for 2,4-Difluoroaniline
2,4-Difluoroaniline manufacturer
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