2,4-Dichloro-6-methoxypyrimidine

CAS NO.：43212-41-5
Empirical Formula: C5H4Cl2N2O
Molecular Weight: 179
MDL number: MFCD00955635
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 00:02:43

What is 2,4-Dichloro-6-methoxypyrimidine?

The Uses of 2,4-Dichloro-6-methoxypyrimidine

2,4-Dichloro-6-methoxypyrimidine is an intermediate used to prepare piperazinyl pyrimidine derivatives as γ-secretase modulators. It is also used in the synthesis of α-azinylalkylamino-substituted (thiazolylamino)pyrimidines and -pyrazines as selective JAK2 inhibitors.

Properties of 2,4-Dichloro-6-methoxypyrimidine

Boiling point:	263.2±20.0 °C(Predicted)
Density	1.446±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
pka	-4.54±0.30(Predicted)

Safety information for 2,4-Dichloro-6-methoxypyrimidine

Signal word	Warning
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H317:Sensitisation, Skin
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P363:Wash contaminated clothing before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. P403:Store in a well-ventilated place.