2,4-Dichloro-6-methoxypyrimidine
- CAS NO.：43212-41-5
- Empirical Formula: C5H4Cl2N2O
- Molecular Weight: 179
- MDL number: MFCD00955635
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 00:02:43
What is 2,4-Dichloro-6-methoxypyrimidine?
The Uses of 2,4-Dichloro-6-methoxypyrimidine
2,4-Dichloro-6-methoxypyrimidine is an intermediate used to prepare piperazinyl pyrimidine derivatives as γ-secretase modulators. It is also used in the synthesis of α-azinylalkylamino-substituted (thiazolylamino)pyrimidines and -pyrazines as selective JAK2 inhibitors.
Properties of 2,4-Dichloro-6-methoxypyrimidine
| Boiling point: | 263.2±20.0 °C(Predicted) |
| Density | 1.446±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -4.54±0.30(Predicted) |
Safety information for 2,4-Dichloro-6-methoxypyrimidine
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P363:Wash contaminated clothing before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention. P403:Store in a well-ventilated place. |
Computed Descriptors for 2,4-Dichloro-6-methoxypyrimidine
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