2,3,5-Triphenyltetrazolium chloride
Synonym(s):TPTZ;TTZ;2,3,5-Triphenyltetrazolium chloride;TTC solution;TTC supplement
- CAS NO.：298-96-4
- Empirical Formula: C19H15ClN4
- Molecular Weight: 334.8
- MDL number: MFCD00011963
- EINECS: 206-071-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-19 08:45:37
What is 2,3,5-Triphenyltetrazolium chloride?
Chemical properties
white powder
The Uses of 2,3,5-Triphenyltetrazolium chloride
2,3,5-Triphenyltetrazolium chloride is a selective serotonin 5-HT4 receptor agonist and 5-HT3 gastrointestinal prokinetic agent for functional dyspepsia
The Uses of 2,3,5-Triphenyltetrazolium chloride
2,3,5-Triphenyl-2H-tetrazolium chloride is used as a dye in cell biological studies.
The Uses of 2,3,5-Triphenyltetrazolium chloride
In analytical chemistry as a sensitive reagent for reducing sugars, and to distinguish between a-ketols and simple aldehydes. For staining plant and animal tissue. Germination indicator in testing the ability of seeds to germinate: G. Lakon, Ber. Dtsch. Bot. Ges. 60, 299, 434 (1942). In histochemical studies. In determination of antibiotics; of dehydrogenases.
Definition
ChEBI: An organic chloride salt having 2,3,5-triphenyltetrazolium as the counterion.
General Description
2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.
Purification Methods
Crystallise TTZ from EtOH or CHCl3, and dry it at 105o. [Beilstein 26 H 363, 26 II 216, 26 III/IV 1774.]
Properties of 2,3,5-Triphenyltetrazolium chloride
| Melting point: | 250 °C(lit.) |
| Boiling point: | 490.96°C (rough estimate) |
| Density | 1.1704 (rough estimate) |
| refractive index | 1.6110 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: may be clear to slightly hazy |
| form | powder |
| color | faint yellow |
| Water Solubility | Soluble in water, ethanol and acetone. Insoluble in ether. |
| λmax | 247 nm |
| Sensitive | Light Sensitive & Hygroscopic |
| Merck | 14,9744 |
| BRN | 3923356 |
| Stability: | Stable. Light sensitive. Protect from moisture. Incompatible with strong oxidizing agents. |
| Biological Applications | Algae viability assay; microbial growth assays; transketolase activity screening assays; detecting bacteria,g-hydroxybutyric acid (GHB),microorganisms,myocardial infarction; measuring dehydrogenase activity; treating cancer |
| CAS DataBase Reference | 298-96-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2,3,5-Triphenyltetrazolium chloride (298-96-4) |
Safety information for 2,3,5-Triphenyltetrazolium chloride
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H228:Flammable solids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,3,5-Triphenyltetrazolium chloride
| InChIKey | PKDBCJSWQUOKDO-UHFFFAOYSA-M |
2,3,5-Triphenyltetrazolium chloride manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 2,3,5-Triphenyltetrazolium chloride, 98% 298-96-4 99%
New Products
DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
2,3,5-Triphenyl-2H-tetrazolium chloride 298-96-4 98%View Details
298-96-4 -
2,3,5-Triphenyltetrazolium chloride, 98% 298-96-4 99%View Details
298-96-4 -
2,3,5-Triphenyltetrazolium Chloride CAS 298-96-4View Details
298-96-4 -
2,3,5-Triphenyltetrazolium Chloride (TTC) extrapure CAS 298-96-4View Details
298-96-4 -
2,3,5-Triphenyltetrazolium chloride CAS 298-96-4View Details
298-96-4 -
2,3,5-Triphenyltetrazolium chloride CAS 298-96-4View Details
298-96-4 -
Tetrazolium salt (TTC) 99% AR CAS 298-96-4View Details
298-96-4 -
TETRAZOLIUM SALT AR CAS 298-96-4View Details
298-96-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.