2,3,4-Trihydroxybenzophenone

The Uses of 2,3,4-Trihydroxybenzophenone

2,3,4-Trihydroxybenzophenone is used in manufacturing method of electrophotographic photosensitive member containing styrene acrylic resin particle and melamine formaldehyde resin particle.

Preparation

Preparation by reaction of benzoic acid with pyrogallol,
in the presence of zinc chloride during 3 h at 145°;
in the presence of Amberlyst-15 (a strongly acid ion exchanger) in chlorobenzene during 10 h at 131–132° (60%);
in the presence of Amberlite IR-120 or Zeokarb 225 (cation exchange resins, sulfonic acid type) during 3 h at 160° (14%);
in the presence of boron trifluoride in ethyl ether at 0° (44%).

Definition

ChEBI: 2,3,4-trihydroxbenzophenone is a benzenetriol that is benzophenone in which one of the phenyl groups is substituted by hydroxy groups at positions 2, 3, and 4. It is a redox mediator. It has a role as a quorum sensing inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor, a human urinary metabolite, a rat metabolite and a drug metabolite. It is a hydroxybenzophenone and a benzenetriol.

General Description

2,3,4-Trihydroxybenzophenone is a hydroxylated benzophenone UV filter and has been quantitated in sea water samples by dispersive liquid-liquid microextraction followed by GC-MS. Estrogenic activity of 2,3,4-trihydroxybenzophenone has been tested by yeast-two hybrid assay.

Flammability and Explosibility

Not classified