2,3-Pyrazinecarboxylic anhydride
Synonym(s):Furo[3,4-b]pyrazine-5,7-dione
- CAS NO.：4744-50-7
- Empirical Formula: C6H2N2O3
- Molecular Weight: 150.09
- MDL number: MFCD00179418
- EINECS: 225-260-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:39
What is 2,3-Pyrazinecarboxylic anhydride?
The Uses of 2,3-Pyrazinecarboxylic anhydride
2,?3-?Pyrazinedicarboxylic Anhydride is a reagent used in the synthesis of highly potent and selective abietane type diterpenoid amides.
Synthesis
Pyrazine-2,3-dicarboxylic acid (4.0 g, 23.8 mmol) was dissolved in acetic anhydride (30 mL).The reaction mixture was refluxed for one hour, and subsequently cooled down to 0 °C in ice bath.The obtained crystals of pyrazine-2,3-dicarboxylic anhydride were filtered off (yield 70%).
Properties of 2,3-Pyrazinecarboxylic anhydride
| Melting point: | 210 °C (dec.)(lit.) |
| Boiling point: | 357.3±22.0 °C(Predicted) |
| Density | 1.686±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Actonitrile (Slightly), DMSO |
| form | Solid |
| pka | -3.43±0.20(Predicted) |
| color | White to light brown crystalline powder |
| CAS DataBase Reference | 4744-50-7(CAS DataBase Reference) |
Safety information for 2,3-Pyrazinecarboxylic anhydride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,3-Pyrazinecarboxylic anhydride
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