2,3-DIHYDROXYQUINOXALINE

Synonym(s):2,3(1H,4H)-Quinoxalinedione;2,3-Quinoxalinediol

CAS NO.：15804-19-0
Empirical Formula: C8H6N2O2
Molecular Weight: 162.15
MDL number: MFCD00006723
EINECS: 239-901-0
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-07 19:09:50

What is 2,3-DIHYDROXYQUINOXALINE?

Chemical properties

off-white powder

The Uses of 2,3-DIHYDROXYQUINOXALINE

2,3-Dihydroxyquinoxaline is a fluorescent reagent and it can be used for the determination of trace Pb(II) in vinegar.

What are the applications of Application

2,3-Dihydroxyquinoxaline can be used:
(1) Basic chemical studies to determine the low-temperature x-ray molecular structure, reciprocal isomerism and spectroscopic properties of 2,3-Dihydroxyquinoxaline^[1].
(2) Quinoline-5-carboxamide derivatives (Vq-Vu) and (VIa-Vu) were prepared by using methyl 2,3-diaminobenzoate as raw material^[2].

General Description

2,3-Dihydroxyquinoxaline(dhq) undergoes electrophilic substitution reaction with sulphuric acid solution and potassium nitrate to form 2,3-dihydroxy-6-nitroquinoxaline. It reacts with Ru₃(CO)₁₂ in DMSO to give the Ru(CO)₂(dhq)(DMSO) complex.

References

[1] SAIED M. SOLIMAN; Morsy A M A Y; J?rg Albering. Low temperature X-ray molecular structure, tautomerism and spectral properties of 2,3-dihydroxyquinoxaline[J]. Journal of Molecular Structure, 2013. DOI:10.1016/j.molstruc.2013.09.005.
[2] KEESARI SRINIVAS. Synthesis, Characterization, and Antibacterial Activity of Novel 2,3-Dihydroxyquinoxaline-5-сarboxamide Derivatives[J]. Russian Journal of Bioorganic Chemistry, 2023. DOI:10.1134/S106816202305014X.

Properties of 2,3-DIHYDROXYQUINOXALINE

Melting point:	>300 °C (lit.)
Boiling point:	288.82°C (rough estimate)
Density	1.3264 (rough estimate)
refractive index	1.5770 (estimate)
storage temp.	Inert atmosphere,Room Temperature
pka	10.66±0.20(Predicted)
form	powder to crystaline
color	White to Orange to Green
BRN	136884
CAS DataBase Reference	15804-19-0(CAS DataBase Reference)
EPA Substance Registry System	2,3-Quinoxalinedione, 1,4-dihydro- (15804-19-0)

Safety information for 2,3-DIHYDROXYQUINOXALINE

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.