2,3'-Dichloroacetophenone
- CAS NO.：21886-56-6
- Empirical Formula: C8H6Cl2O
- Molecular Weight: 189.04
- MDL number: MFCD07783975
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 22:44:32
What is 2,3'-Dichloroacetophenone?
The Uses of 2,3'-Dichloroacetophenone
2,3''-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors.
Properties of 2,3'-Dichloroacetophenone
| Boiling point: | 283.7±20.0 °C(Predicted) |
| Density | 1.310±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| color | White |
| CAS DataBase Reference | 21886-56-6(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanone, 2-chloro-1-(3-chlorophenyl)- (21886-56-6) |
Safety information for 2,3'-Dichloroacetophenone
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for 2,3'-Dichloroacetophenone
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