2,2,2,4'-TETRAFLUOROACETOPHENONE
Synonym(s):α,α,α,4-Tetrafluoroacetophenone
- CAS NO.：655-32-3
- Empirical Formula: C8H4F4O
- Molecular Weight: 192.11
- MDL number: MFCD00042393
- EINECS: 211-509-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:21:18
What is 2,2,2,4'-TETRAFLUOROACETOPHENONE?
The Uses of 2,2,2,4'-TETRAFLUOROACETOPHENONE
2,2,2,4''-Tetrafluoroacetophenone is used in the stereoselective synthesis of trifluoromethyl-substituted 2H-furan-amines.
General Description
2,2,2,4′-Tetrafluoroacetophenone (α,α,α,4-Tetrafluoroacetophenone, 2,2,2-trifluoro-1-(4-fluorophenyl)ethanone) is a fluorinated building block. Its enthalpy of vaporization at boiling point has been reported.
Properties of 2,2,2,4'-TETRAFLUOROACETOPHENONE
| Melting point: | 24-27 °C(lit.) |
| Boiling point: | 66-67 °C34 mm Hg(lit.) |
| Density | 1.37 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 90 °F |
| storage temp. | Sealed in dry,2-8°C |
| form | powder to lump to clear liquid |
| Specific Gravity | 1.370 |
| color | White or Colorless to Light yellow |
| λmax | 266nm(2-Propanol)(lit.) |
| BRN | 1872824 |
| CAS DataBase Reference | 655-32-3(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanone, 2,2,2-trifluoro-1-(4-fluorophenyl)- (655-32-3) |
Safety information for 2,2,2,4'-TETRAFLUOROACETOPHENONE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H228:Flammable solids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2,2,4'-TETRAFLUOROACETOPHENONE
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