2,2,2-Trifluoroethylamine
Synonym(s):2-Amino-1,1,1-trifluoroethane
- CAS NO.：753-90-2
- Empirical Formula: C2H4F3N
- Molecular Weight: 99.06
- MDL number: MFCD00008132
- EINECS: 212-041-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:55:06
What is 2,2,2-Trifluoroethylamine?
Chemical properties
clear colorless liquid
The Uses of 2,2,2-Trifluoroethylamine
2,2,2-Trifluoroethylamine was used in the determination of ibuprofen (2-(p-isobutylphenyl)propionic acid), a non-steroid anti-inflammatory drug (NSAID) residue in surface and wastewater samples.
The Uses of 2,2,2-Trifluoroethylamine
2,2,2-Trifluoroethanamine is a reagent used in chemical synthesis.
What are the applications of Application
2,2,2-Trifluoroethylamine is a catalyst for the isomerisation of unsaturated ketones
Synthesis Reference(s)
Canadian Journal of Chemistry, 32, p. 639, 1954 DOI: 10.1139/v54-083
General Description
2,2,2-Trifluoroethylamine, a volatile organic compound, was tested using corona discharge ion mobility spectrometry with orthogonal acceleration time of flight mass spectrometry (CD IMS-oaTOF).
Safety Profile
Low toxicity by inhalation.Corrosive. Highly flammable liquid. When heated todecomposition it emits very toxic fumes of F?? and NOx.
Properties of 2,2,2-Trifluoroethylamine
| Boiling point: | 36-37 °C(lit.) |
| Density | 1.262 g/mL at 20 °C(lit.) |
| vapor pressure | ~7.6 psi ( 20 °C) |
| refractive index | n |
| Flash point: | 2 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| pka | 5.47±0.30(Predicted) |
| Specific Gravity | 1.245 |
| color | Clear colorless |
| BRN | 1733204 |
| CAS DataBase Reference | 753-90-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,2,2-Trifluoroethylamine(753-90-2) |
| EPA Substance Registry System | Ethanamine, 2,2,2-trifluoro- (753-90-2) |
Safety information for 2,2,2-Trifluoroethylamine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H302:Acute toxicity,oral H314:Skin corrosion/irritation H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2,2-Trifluoroethylamine
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