2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol

CAS NO.：1027512-47-5
Empirical Formula: C49H54F17N2O9P
Molecular Weight: 1168.91
MDL number: MFCD08062091
Update Date: 2026-09-12 18:55:54

What is 2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol?

The Uses of 2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol

F-CPR-II CEP allows a combination of fluorous affinity purification with concomitant 5''-phosphorylation, which is especially attractive when synthesizing longmers that will be used in ligase reactions. It may also be utilized as a common handle for fluorous purification, obviating the need to choose a different fluorous phosphoramidite for each different 5''-terminal nucleotide when a 5''-phosphate is tolerated in a particular application.

Properties of 2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol

Boiling point:	813.7±65.0 °C(Predicted)
pka	2.85±0.70(Predicted)

Safety information for 2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol

Computed Descriptors for 2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol

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