2,2'-Biphenol
Synonym(s):2,2′-Biphenyldiol;2,2′-Dihydroxybiphenyl;2,2′-Diphenol;Biphenyl-2,2′-diol;o,o′-Biphenol, 2,2′-Dihydroxydiphenyl
- CAS NO.：1806-29-7
- Empirical Formula: C12H10O2
- Molecular Weight: 186.21
- MDL number: MFCD00002210
- EINECS: 217-303-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:02
What is 2,2'-Biphenol?
Chemical properties
Beige to greyish-beige powder
The Uses of 2,2'-Biphenol
2,2'-Dihydroxybiphenyl, is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.
Definition
ChEBI: A member of the class of hydroxybiphenyls carrying hydroxy groups at positions 2 and 2'.
Production Methods
2,2'-Dihydroxybiphenyl is obtained by alkaline fusion of biphenylene oxide at ca. 300 ℃ (sometimes catalyzed by fluorene or carbazole) or by debutylation of 3,3',5,5'-tetra-tert-butyl-2,2'-dihydroxybiphenyl, which itself is produced by the oxidative coupling of 2,4-di-tert-butylphenol. 2,2'-Dihydroxy-5,5'-dimethylbiphenyl can be synthesized accordingly.
Safety Profile
Poison by intraperitoneal andintravenous routes. Human mutation data reported. Whenheated to decomposition it emits acrid smoke andirritating fumes.
Purification Methods
Crystallise the biphenyl repeatedly from toluene, then sublime it at 60o/10-4mm. [Beilstein 6 IV 6645.]
Properties of 2,2'-Biphenol
| Melting point: | 108-110 °C |
| Boiling point: | 315 °C(lit.) |
| Density | 0.83 |
| refractive index | 1.6086 (estimate) |
| Flash point: | 154 °C |
| storage temp. | Store below +30°C. |
| form | Powder |
| pka | 7.32±0.10(Predicted) |
| color | Beige to grayish-beige |
| Water Solubility | insoluble |
| BRN | 1638363 |
| CAS DataBase Reference | 1806-29-7(CAS DataBase Reference) |
| NIST Chemistry Reference | [1,1'-Biphenyl]-2,2'-diol(1806-29-7) |
| EPA Substance Registry System | 2,2'-Biphenol (1806-29-7) |
Safety information for 2,2'-Biphenol
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2,2'-Biphenol
| InChIKey | IMHDGJOMLMDPJN-UHFFFAOYSA-N |
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