2,2'-Bicinchoninic Acid
Synonym(s):2,2′-Bicinchoninic acid
- CAS NO.：1245-13-2
- Empirical Formula: C20H12N2O4
- Molecular Weight: 344.32
- MDL number: MFCD00068342
- EINECS: 214-990-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:22:27
What is 2,2'-Bicinchoninic Acid?
Chemical properties
Beige powder
The Uses of 2,2'-Bicinchoninic Acid
2,2′-Biquinoline-4,4′-dicarboxylic acid has been used in a study that synthesized and structurally characterized six metal-organic coordination polymers.
What are the applications of Application
2,2′-Bicinchoninic Acid is has been used in laboratories as a photometric reagent in protein assays
Purification Methods
Dissolve the acid in dilute NaOH and precipitate it with acetic acid, filter, wash swell with H2O and dry it at 100o in a vacuum oven. Attempts to form a picrate failed. The methyl ester (SOCl2-MeOH) has m 165.6-166o. [Lesesne & Henze J Am Chem Soc 64 1897 1942, Brown et al. J Am Chem Soc 68 2705 1946, Beilstein 25 III/IV 1148.] For the di-K salt see entry in “Metal-organic Compounds” in Chapter 5.
Properties of 2,2'-Bicinchoninic Acid
| Melting point: | 365°C(lit.) |
| Boiling point: | 626.2±55.0 °C(Predicted) |
| Density | 1.468±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 1.77±0.10(Predicted) |
| color | Light yellow to Yellow to Orange |
| BRN | 321561 |
| InChI | InChI=1S/C20H12N2O4/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18/h1-10H,(H,23,24)(H,25,26) |
| CAS DataBase Reference | 1245-13-2(CAS DataBase Reference) |
| EPA Substance Registry System | [2,2'-Biquinoline]-4,4'-dicarboxylic acid (1245-13-2) |
Safety information for 2,2'-Bicinchoninic Acid
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02 |
| GHS Hazard Statements |
H225:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for 2,2'-Bicinchoninic Acid
| InChIKey | AFYNADDZULBEJA-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)C(C(O)=O)=CC=1C1C=C(C(O)=O)C2C(N=1)=CC=CC=2 |
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