2,2′-Azobis(2-methylpropionamidine) dihydrochloride
Synonym(s):α,α′-Azodiisobutyramidine dihydrochloride;AAPH;AAPH - CAS 2997-92-4 - Calbiochem;ABAP, 2,2ʹ-Azobis-(2-amidinopropane), 2HCl, 2,2ʹ-Azobis-(2-methylpropionamidine), 2HCl
- CAS NO.：2997-92-4
- Empirical Formula: C8H20Cl2N6
- Molecular Weight: 271.19
- MDL number: MFCD00142725
- EINECS: 221-070-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:21:41
What is 2,2′-Azobis(2-methylpropionamidine) dihydrochloride?
Chemical properties
light yellow crystalline powder
The Uses of 2,2′-Azobis(2-methylpropionamidine) dihydrochloride
2,2'-Azobis(2-methylpropionamidine) dihydrochloride can be used as free radical initiator, apoptosis inducer.
The Uses of 2,2′-Azobis(2-methylpropionamidine) dihydrochloride
2,2'-Azobis(2-methylpropionamidine) dihydrochloride is used to prepare Resveratrol and its analogues for use as antioxidants. Also acts as an antioxidant.
The Uses of 2,2′-Azobis(2-methylpropionamidine) dihydrochloride
Free radical initiator.
Polymerization initiator for acrylic, vinyl and allyl monomers.
Definition
ChEBI: AAPH is an azo compound.
Flammability and Explosibility
Non flammable
Safety Profile
Poison by ingestion. A skinirritant. When heated to decomposition it emits toxicvapors of NOx and HCl.
Properties of 2,2′-Azobis(2-methylpropionamidine) dihydrochloride
| Melting point: | 175-177 °C(lit.) |
| Density | 0.42 |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | 0-6°C |
| solubility | acetone, dioxane, methanol, ethanol, DMSO and water: soluble |
| form | granular |
| color | White to off-white |
| Water Solubility | 176.2g/L at 20℃ |
| Stability: | Unstable. Sensitive to heat and light. Incompatible with strong oxidizing agents, strong acids. |
| CAS DataBase Reference | 2997-92-4(CAS DataBase Reference) |
| EPA Substance Registry System | Propanimidamide, 2,2'-azobis[2-methyl-, dihydrochloride (2997-92-4) |
Safety information for 2,2′-Azobis(2-methylpropionamidine) dihydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H251:Self-heating substances and mixtures H302:Acute toxicity,oral H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P235:Keep cool. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2′-Azobis(2-methylpropionamidine) dihydrochloride
| InChIKey | LXEKPEMOWBOYRF-QDBORUFSSA-N |
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![2,2'-AZOBIS[2-METHYL-N-(2-HYDROXYETHYL)PROPIONAMIDE]](https://img.chemicalbook.in/CAS/GIF/61551-69-7.gif)
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