2-(Trifluoromethyl)acrylic acid
Synonym(s):TFMAA
- CAS NO.：381-98-6
- Empirical Formula: C4H3F3O2
- Molecular Weight: 140.06
- MDL number: MFCD00042424
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:44
What is 2-(Trifluoromethyl)acrylic acid?
Chemical properties
LIGHT YELLOW TRANSPARENT CHUNKS
The Uses of 2-(Trifluoromethyl)acrylic acid
2-(Trifluoromethyl)acrylic acid is used as an acidic functional monomer for molecular imprinting of nicotine. And also used in the conventional functional monomer methacrylic acid.
The Uses of 2-(Trifluoromethyl)acrylic acid
2-(Trifluoromethyl)acrylic acid (TFMAA) is a strong acid functional monomer, which shows a good performance in the solid-phase extraction of domoic acid. It can also be used in the preparation of molecularly imprinted polymers that show diastereoselectivity for cinchona alkaloids.
Properties of 2-(Trifluoromethyl)acrylic acid
| Melting point: | 51-52 °C (lit.) |
| Boiling point: | 86 °C |
| Density | 1.3949 (estimate) |
| Flash point: | 179 °F |
| storage temp. | 2-8°C |
| pka | 2.07±0.11(Predicted) |
| form | Chunks |
| color | Light yellow |
| Water Solubility | Soluble in water. |
| CAS DataBase Reference | 381-98-6(CAS DataBase Reference) |
Safety information for 2-(Trifluoromethyl)acrylic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(Trifluoromethyl)acrylic acid
| InChIKey | VLSRKCIBHNJFHA-UHFFFAOYSA-N |
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