2-Thiophenemethylamine

Chemical properties

Clear yellow liquid

The Uses of 2-Thiophenemethylamine

2-Thiophenemethylamine can be used as areactant involved in synthesis of Triazole-linked-thiopene conjugates and a biomimetic model for studies of metal detoxification and oxidative stress involving metallothionein.

The Uses of 2-Thiophenemethylamine

2-Thiophenemethylamine is Reactant involved in synthesis of: Triazole-linked-thiopene conjugates. It is used for biomimetic model for studies of metal detoxification and oxidative stress involving metallothionein.It is a reactant involved in studies of organocatalyzed asymmetric reductive amination of ketones.

The Uses of 2-Thiophenemethylamine

Reactant involved in synthesis of:

• Triazole-linked-thiopene conjugates for use as a biomimetic model for studies of metal detoxification and oxidative stress involving metallothionein
• Serotonin 5-HT1A receptor antagonists which have neuroprotective affects against ischemic cell damage
• Imidazole- and piperonyl-containing thiadiazoles and pyrimidines for use as inducible oxide synthase dimerization inhibitors
• Optoelectronic segmented polyurethanes

• Studies of organocatalyzed asymmetric reductive amination of ketones
• Metal-free aerobic oxidative coupling of amines to imines

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1389, 1946 DOI: 10.1021/ja01211a510

General Description

2-Thiophenemethylamine is a potential ligand replacement for poly(3-hexylthiophene)/CdSe hybrid solar cells.

Purification Methods

Distil the amine under reduced pressure (nitrogen), from BaO, through a column packed with glass helices. The hydrochloride has m 193-194o (from EtOH/Me2CO) and the picrate has m 181-182o. [Beilstein 18 III/IV 7096.]