2-Pyrazinylethanethiol
Synonym(s):Mercaptoethylpyrazine
- CAS NO.：35250-53-4
- Empirical Formula: C6H8N2S
- Molecular Weight: 140.21
- MDL number: MFCD00053160
- EINECS: 237-246-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-03 14:17:14
What is 2-Pyrazinylethanethiol?
Chemical properties
Colorless liquid
Chemical properties
Pyrazine ethanethiol has a sulfurous, meaty, cabbage odor.
The Uses of 2-Pyrazinylethanethiol
2-(2-Mercaptoethyl)pyrazine is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals, petrochemicals and dyestuff. It is used as a flavoring agent has a sulfurous type odor and a meaty type flavor.
Preparation
From 2-vinylpyrazine by reaction with thiolactic acid, followed by conversion of the thiolester to 2-(pyrazinyl) ethanethiol.
Taste threshold values
Taste characteristics at 2 ppm: meaty, sulfurous, pot roast and savory with nuances suitable for chicken and pork.
Properties of 2-Pyrazinylethanethiol
| Boiling point: | 105-110 °C20 mm Hg(lit.) |
| Density | 1.142 g/mL at 25 °C(lit.) |
| refractive index | n |
| FEMA | 3230 | PYRAZINE ETHANETHIOL |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,2-8°C |
| form | clear liquid |
| pka | 9.82±0.10(Predicted) |
| color | White to Yellow to Green |
| Odor | at 0.10 % in propylene glycol. sulfurous meaty cabbage |
| Water Solubility | Partly soluble in water, soluble in most organic solvents. |
| JECFA Number | 795 |
| CAS DataBase Reference | 35250-53-4(CAS DataBase Reference) |
| EPA Substance Registry System | Pyrazineethanethiol (35250-53-4) |
Safety information for 2-Pyrazinylethanethiol
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Pyrazinylethanethiol
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