2-Picolylamine
Synonym(s):2-(Aminomethyl)pyridine
- CAS NO.：3731-51-9
- Empirical Formula: C6H8N2
- Molecular Weight: 108.14
- MDL number: MFCD00006360
- EINECS: 223-090-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:28:41
What is 2-Picolylamine?
Chemical properties
clear colorless to yellow or orange liquid
The Uses of 2-Picolylamine
2-Picolylamine is a bihaptic amine that can be used:
- As a key precursor to synthesize various ionic liquids through the formation of β-amino alcohols as intermediates.
- As a chelating ligand for the synthesis of complexes such as zinc picolylamine complex and Cu(II) picolylamine complex.
- To functionalize poly(styrene-co-maleic anhydride) (PSMA) resin to facilitate the adsorption of uranium from aqueous solution.
The Uses of 2-Picolylamine
2-Picolylamine may be used as a derivatization agent to enhance the sensitivity of carboxylic acids and short-chain fatty acids for their determination in biological samples by liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) and ultra-high performance liquid chromatography (UHPLC), respectively.
What are the applications of Application
2-Picolylamine is a synthesis reagent used in the synthesis of PPD analogues
Definition
ChEBI: 2-Pyridinemethanamine is a member of pyridines.
General Description
2-Picolylamine, a bihaptic nucleophile, is a bidentate ligand that is generally utilized for the preparation of various multidentate ligands and the corresponding complexes.
Properties of 2-Picolylamine
| Melting point: | 20°C |
| Boiling point: | 82-85 °C12 mm Hg(lit.) |
| Density | 1.049 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 194 °F |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| form | Liquid |
| pka | pK1: 2.31(+2);pK2: 8.79(+1) (25°C,μ=0.5) |
| color | Clear colorless to yellow or orange |
| PH | 11-12 (100g/l, H2O, 20℃) |
| Water Solubility | SOLUBLE |
| Sensitive | Air Sensitive |
| BRN | 108054 |
| CAS DataBase Reference | 3731-51-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Pyridinemethanamine(3731-51-9) |
| EPA Substance Registry System | 2-Pyridinemethanamine (3731-51-9) |
Safety information for 2-Picolylamine
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Picolylamine
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