2-Nitroethanol
- CAS NO.：625-48-9
- Empirical Formula: C2H5NO3
- Molecular Weight: 91.07
- MDL number: MFCD00007405
- EINECS: 210-895-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-10 10:27:20
What is 2-Nitroethanol?
Chemical properties
Clear yellow liquid
The Uses of 2-Nitroethanol
2-Nitroethanol is an aliphatic β-nitro alcohol used as an in vivo therapeutic corneoscleral crosslinking agents with higher order nitroalcohol. It also functions as a crosslinking reagent for scieral tissue cross-linking of the eye cornea for treating keratoconus and post-surgical keratectasia.
General Description
Mobile dark brown-red liquid with a pungent odor.
Air & Water Reactions
Hygroscopic. Insoluble in water.
Reactivity Profile
2-Nitroethanol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. 2-Nitroethanol has exploded under vacuum distillation(attributed to the presence of peroxides or alkali).
Fire Hazard
2-Nitroethanol is probably combustible.
Properties of 2-Nitroethanol
| Melting point: | -80 °C (lit.) |
| Boiling point: | 194 °C/765 mmHg (lit.) |
| Density | 1.27 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform, DMSO, Methanol (Sparingly) |
| form | Liquid |
| pka | 8.42±0.29(Predicted) |
| color | Clear yellow |
| BRN | 1633753 |
| CAS DataBase Reference | 625-48-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanol, 2-nitro-(625-48-9) |
| EPA Substance Registry System | 2-Nitroethanol (625-48-9) |
Safety information for 2-Nitroethanol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Nitroethanol
2-Nitroethanol manufacturer
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