2-Naphthyl phosphate monosodium salt
Synonym(s):β-Naphthyl phosphate monosodium salt;2-Naphthyl phosphate monosodium salt;mono-Sodium 2-naphthyl phosphate sodium salt
- CAS NO.：14463-68-4
- Empirical Formula: C10H8NaO4P
- Molecular Weight: 246.13
- MDL number: MFCD00065914
- EINECS: 238-452-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:49
What is 2-Naphthyl phosphate monosodium salt?
The Uses of 2-Naphthyl phosphate monosodium salt
2-Naphthyl Phosphate, Monosodium Salt can be used as reagent/reactant in preparation mono, di and tri-?mannopyranosyl phosphates as mannose-?1-?phosphate prodrugs for potential CDG-?Ia therapy.
Purification Methods
Recrystallise it from H2O (10mL) containing NaCl (0.4g). The salt is collected by centrifugation and dried in a vacuum desiccator, m 203-205o (partially resolidifies and re-melts at 244o). It crystallises from MeOH (m 222-223o). The free acid is recrystallised several times by addition of 2.5 parts of hot CHCl3 to a hot solution of the free acid (1 part) in Me2CO (1.3 parts), m 177-178o. [Friedman & Seligmann J Am Chem Soc 73 5292 1951, Chanley & Feaggeson J Am Chem Soc 77 4002 1955, Beilstein 6 H 647, 6 III 2989, 6 IV 428.] See also entry on p 688 in Chapter 6.
Properties of 2-Naphthyl phosphate monosodium salt
| storage temp. | -20°C |
| BRN | 3779148 |
| CAS DataBase Reference | 14463-68-4(CAS DataBase Reference) |
Safety information for 2-Naphthyl phosphate monosodium salt
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Naphthyl phosphate monosodium salt
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