2-Methylhydroquinone
Synonym(s):2,5-Dihydroxytoluene, Toluhydroquinone;2-Methylhydroquinone;Toluhydroquinone
- CAS NO.：95-71-6
- Empirical Formula: C7H8O2
- Molecular Weight: 124.14
- MDL number: MFCD00002345
- EINECS: 202-443-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:35
What is 2-Methylhydroquinone?
Chemical properties
white solid
The Uses of 2-Methylhydroquinone
Antioxidant, polymerization inhibitor.
The Uses of 2-Methylhydroquinone
Methylhydroquinone is used as stabilizer and antioxidant in aerylic monomers to prevent polymerization.
The Uses of 2-Methylhydroquinone
Methylhydroquinone is a marine fungus metabolite, showing activity as an angiosupressor that interferes with the Akt pathway. Allows for screening of novel inhibitors of angiogenesis.
Definition
ChEBI: A member of the class of hydroquinones that is hydroquinone in which one of the benzene hydrogens has been replaced by a methyl group.
Synthesis Reference(s)
Tetrahedron, 44, p. 1227, 1988 DOI: 10.1016/S0040-4020(01)85902-0
Tetrahedron Letters, 22, p. 2337, 1981 DOI: 10.1016/S0040-4039(01)82900-2
General Description
Methylhydroquinone is produced by the oxidation of o-cresol by the mutants G103S, G103S/A107G, and G103S/A107T.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Methylhydroquinone (Toluquinol) inhibits the growth of endothelial and tumor cells in culture in the micromolar range and is a promising drug candidate in the treatment of cancer and other angiogenesis-related pathologies.
Purification Methods
Crystallise the quinone from EtOH. [Beilstein 6 IV 5866.]
Properties of 2-Methylhydroquinone
| Melting point: | 128-130 °C(lit.) |
| Boiling point: | 285°C |
| Density | 1.1006 (rough estimate) |
| vapor pressure | 0.004Pa at 25℃ |
| refractive index | 1.4922 (estimate) |
| Flash point: | 172 °C |
| storage temp. | Store below +30°C. |
| solubility | 77g/l |
| form | Crystalline Powder |
| pka | pK1:10.03;pK2:11.62 (25°C) |
| color | Grayish-white to light beige |
| Water Solubility | 77 g/L (25 ºC) |
| BRN | 2041489 |
| Stability: | Stable. Combustible. Incompatible with oxidizing agents, strong bases. |
| CAS DataBase Reference | 95-71-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,4-Benzenediol, 2-methyl-(95-71-6) |
| EPA Substance Registry System | 2-Methylhydroquinone (95-71-6) |
Safety information for 2-Methylhydroquinone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Methylhydroquinone
| InChIKey | CNHDIAIOKMXOLK-UHFFFAOYSA-N |
2-Methylhydroquinone manufacturer
Kavya Pharma
Gujarat
Phone:91-7567426252
Whatsapp: 91-7567426252
product: Toluhydroquinone cas 95-71-6, 99%
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