2-Methylglutaric Acid

Synonym(s):2-Methylglutaric acid;2-Methylpentanedioic acid

CAS NO.：617-62-9
Empirical Formula: C6H10O4
Molecular Weight: 146.14
MDL number: MFCD00002661
EINECS: 210-521-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 05:59:16

What is 2-Methylglutaric Acid?

Description

(2)-Methylglutaric acid is a metabolite found in or produced by Saccharomyces cerevisiae. It is used in of sparsely pillared organic-inorganic hybrid compound.

The Uses of 2-Methylglutaric Acid

2-Methylglutaric acid is used as primary and secondary intermediates in pharmaceutical and chemical research.

Definition

ChEBI: 2-methylglutaric acid is an alpha,omega-dicarboxylic acid that is glutaric acid substituted at position 2 by a methyl group. It has a role as a mammalian metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is functionally related to a glutaric acid. It is a conjugate acid of a 2-methylglutarate(2-).

Flammability and Explosibility

Non flammable

References

1. Effects of Relative Humidity and Particle Phase Water on the Heterogeneous OH Oxidation of 2-Methylglutaric Acid Aqueous Droplets. DOI:10.1021/acs.jpca.6b11606
2. Synthesis of 2‐Methylglutaric Acid by Oxidation of 3‐Methyl‐1,2‐ cyclopentanedione on Anodically Generated Ce(IV). DOI:10.1002/chin.199538117

Properties of 2-Methylglutaric Acid

Melting point:	80-82 °C(lit.)
Boiling point:	214-215 °C22 mm Hg(lit.)
Density	1.246
vapor pressure	0.001Pa at 20℃
Flash point:	149℃
storage temp.	Store below +30°C.
solubility	DMF: 20 mg/ml; DMSO: 16 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 10 mg/ml
form	powder to crystal
pka	4.57±0.10(Predicted)
color	White to Light yellow
Water Solubility	Soluble in water.
InChI	InChI=1S/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)
EPA Substance Registry System	2-Methylglutaric acid (617-62-9)

Safety information for 2-Methylglutaric Acid

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H314:Skin corrosion/irritation H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.