2-METHYL-6-NITROBENZOIC ANHYDRIDE
Synonym(s):MNBA
- CAS NO.：434935-69-0
- Empirical Formula: C16H12N2O7
- Molecular Weight: 344.28
- MDL number: MFCD06797117
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:22:27
What is 2-METHYL-6-NITROBENZOIC ANHYDRIDE?
The Uses of 2-METHYL-6-NITROBENZOIC ANHYDRIDE
2-Methyl-6-nitrobenzoic anhydride can be used:
- As a versatile lactonization reagent applicable in the preparation of varieties of macrolide natural products and lactones.
- As a reaction promoter in the synthesis of carboxamide derivatives by using corresponding amines and carboxylic acids.
- In the total synthesis of GRP78 inhibitor prunustatin A, antifungal compound (3R,16E,20E,23R)-(?)-eushearilide and an antiobestic drug tetrahydrolipstatin.
General Description
2-Methyl-6-nitrobenzoic anhydride is a reagent employed as a coupling promoter in the synthesis of amides, lactones, esters, and peptides.
Properties of 2-METHYL-6-NITROBENZOIC ANHYDRIDE
| Melting point: | 173-177 °C |
| Boiling point: | 559.4±50.0 °C(Predicted) |
| Density | 1.416±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | very faint turbidity in hot Toluene |
| form | powder to crystal |
| color | White to Yellow to Orange |
Safety information for 2-METHYL-6-NITROBENZOIC ANHYDRIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-METHYL-6-NITROBENZOIC ANHYDRIDE
| InChIKey | YEKPNMQQSPHKBP-UHFFFAOYSA-N |
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