2-Methyl-4-methoxybenzenamine

Synonym(s):m-Cresidine;2-Methyl-p-anisidine

CAS NO.：102-50-1
Empirical Formula: C8H11NO
Molecular Weight: 137.18
MDL number: MFCD00007735
EINECS: 203-036-7
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 00:45:55

2-Methyl-4-methoxybenzenamine Structural

What is 2-Methyl-4-methoxybenzenamine?

Chemical properties

brick red crystals or liquid

The Uses of 2-Methyl-4-methoxybenzenamine

4-Methoxy-2-methylaniline is a reagent used in organic synthesis of more complex compounds that have a more specific function. For example, enzyme inhibitors.

Definition

ChEBI: Meta-Cresidine is a member of methoxybenzenes.

General Description

Crystals or brick red liquid.

Air & Water Reactions

Sensitive to prolonged exposure to air and light. Insoluble in water.

Reactivity Profile

2-Methyl-4-methoxybenzenamine neutralizes acids in weakly exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Reacts with oxidizing agents .

Health Hazard

ACUTE/CHRONIC HAZARDS: 2-Methyl-4-methoxybenzenamine is a local irritant. When heated to decomposition it emits toxic fumes of NOx. 2-Methyl-4-methoxybenzenamine is an experimental animal carcinogen.

Fire Hazard

2-Methyl-4-methoxybenzenamine is probably combustible.

Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Properties of 2-Methyl-4-methoxybenzenamine

Melting point:	13-14 °C(lit.)
Boiling point:	248-249 °C(lit.)
Density	1.065 g/mL at 25 °C(lit.)
refractive index	n20/D 1.565(lit.)
Flash point:	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Acetonitrile (Slightly), Chloroform (Slightly), DMSO, Methanol (Slightly)
form	Oil
pka	5.05±0.10(Predicted)
color	Light Brown to Very Dark Red
Water Solubility	insoluble, <0.1 g/100 mL at 21.5 ºC
BRN	774727
Stability:	Stable. May be light or air-sensitive. Combustible. Incompatible with acids, strong oxidizing agents.
CAS DataBase Reference	102-50-1(CAS DataBase Reference)
IARC	3 (Vol. 27, Sup 7) 1987
NIST Chemistry Reference	Benzenamine, 4-methoxy-2-methyl-(102-50-1)
EPA Substance Registry System	m-Cresidine (102-50-1)

Safety information for 2-Methyl-4-methoxybenzenamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.