2-Methyl-1,3-dithiane

CAS NO.：6007-26-7
Empirical Formula: C5H10S2
Molecular Weight: 134.26
MDL number: MFCD00014652
EINECS: 227-859-6
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:52:03

What is 2-Methyl-1,3-dithiane?

The Uses of 2-Methyl-1,3-dithiane

It has been employed in the synthesis of methyl ketones. 2-Methyl-1,3-dithiane is suitable for use in the preparation of potassium trifluoro(2-methyl-1,3-dithiano)borate.

Synthesis Reference(s)

Tetrahedron Letters, 27, p. 6305, 1986 DOI: 10.1016/S0040-4039(00)87793-X

General Description

2-Methyl-1,3-dithiane is a versatile acyl anion equivalent. Role of hyperconjugation in the conformational analysis of 2-methyl-1,3-dithiane has been reported.

Purification Methods

Wash the dithiane with H2O, 2.5 M aqueous NaOH, H2O, brine, dry over K2CO3 (use toluene as solvent if the volume of reagent is small), filter, evaporate and distil the colourless residue. IR film: 1455, 1371 and 1060 (all medium and CH3), 1451m, 1422s, 1412m, 1275m, 1236m, max 1190m, 1171w, 918m and 866w (all dithiane) cm-1 [Corey & Erickson J Org Chem 36 3553 1971, Seebach & Corey J Org Chem 40 231 1975]. [Beilstein 19 III/IV 49, 19/1 V 53.]

Properties of 2-Methyl-1,3-dithiane

Boiling point:	56-59 °C/3 mmHg (lit.)
Density	1.121 g/mL at 25 °C (lit.)
refractive index	n20/D 1.560(lit.)
Flash point:	180 °F
form	Liquid
color	Colorless to brown
Odor	at 0.10 % in dipropylene glycol. sulfurous
Water Solubility	Not miscible or difficult to mix in water. Soluble in alcohol.
BRN	102766
CAS DataBase Reference	6007-26-7(CAS DataBase Reference)

Safety information for 2-Methyl-1,3-dithiane

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H227:Flammable liquids
Precautionary Statement Codes	P403+P235:Store in a well-ventilated place. Keep cool.