2-METHOXYETHYLAMINE
Synonym(s):2-Aminoethyl methyl ether;2-Methoxyethylamine
- CAS NO.：109-85-3
- Empirical Formula: C3H9NO
- Molecular Weight: 75.11
- MDL number: MFCD00008180
- EINECS: 203-712-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-28 17:20:35
What is 2-METHOXYETHYLAMINE?
Chemical properties
clear colorless liquid
The Uses of 2-METHOXYETHYLAMINE
2-Methoxyethylamine is used as a reagent in the preparation of lipid-like materials for delivery of RNAi therapeutics.
What are the applications of Application
2-Methoxyethylamine is an amino alcohol
General Description
Kinetics of reaction of 2-methoxyethylamine with guanosine 5′-phospho-2-methylimidazolide (2-MeImpG) was studied.
Purification Methods
An aqueous 70% solution of the amine is dehydrated by azeotropic distillation with *benzene or methylene chloride and the amine is distilled twice from zinc dust. Store it in a tight container as it absorbs CO2 from the atmosphere. [Beilstein 4 IV 1411.]
Properties of 2-METHOXYETHYLAMINE
| Melting point: | -82 °C |
| Boiling point: | 95 °C (lit.) |
| Density | 0.864 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 49 °F |
| storage temp. | Store below +30°C. |
| Water Solubility | Completely miscible in water |
| form | clear liquid |
| pka | 9.89(at 10℃) |
| color | Colorless to Almost colorless |
| PH | 12 (100g/l, H2O, 20℃) |
| explosive limit | 3-16.10%(V) |
| BRN | 741854 |
| CAS DataBase Reference | 109-85-3(CAS DataBase Reference) |
| EPA Substance Registry System | Ethanamine, 2-methoxy- (109-85-3) |
Safety information for 2-METHOXYETHYLAMINE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. |
Computed Descriptors for 2-METHOXYETHYLAMINE
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