2-Methoxyestrone
Synonym(s):2-MeO-E1;3-Hydroxy-2-methoxyestra-1,3,5(10)-trien-17-one
- CAS NO.：362-08-3
- Empirical Formula: C19H24O3
- Molecular Weight: 300.39
- MDL number: MFCD00056413
- EINECS: 206-645-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:53:39
What is 2-Methoxyestrone?
The Uses of 2-Methoxyestrone
2-Methoxyestrone is a endogenous estrogen metabolite. 2-Methoxyestrone detection can be used as a breast cancer biomarker and help assess the risk-factors for development of breast cancer.
Definition
ChEBI: A 17-oxo steroid that is estrone in which the hydrogen at position 2 is substituted by a methoxy group.
Properties of 2-Methoxyestrone
| Melting point: | 187.0-189.5 °C |
| Boiling point: | 463.5±45.0 °C(Predicted) |
| Density | 1.172±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform: slightly soluble |
| form | neat |
| pka | 10.27±0.40(Predicted) |
| form | Solid |
| color | White to off-white |
| optical activity | [α]/D +182.5±7.5°, c = 0.5 in methanol |
Safety information for 2-Methoxyestrone
| Signal word | Warning |
| Pictogram(s) |
 Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H351:Carcinogenicity H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P273:Avoid release to the environment. P308+P313:IF exposed or concerned: Get medical advice/attention. |
Computed Descriptors for 2-Methoxyestrone
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