2-Methoxy-3-sec-butyl pyrazine

Synonym(s):2-sec-Butyl-3-methoxypyrazine

CAS NO.：24168-70-5
Empirical Formula: C9H14N2O
Molecular Weight: 166.22
MDL number: MFCD00006136
EINECS: 246-050-9
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 03:22:38

2-Methoxy-3-sec-butyl pyrazine Structural

What is 2-Methoxy-3-sec-butyl pyrazine?

Description

2-Methoxy-3-(l-methylpropyl)pyrazine is like green peas, galbarum oil, bell pepper. Prepared by condensation of isolencine amide with glyoxal, followed by methylation with CH2N2.

Chemical properties

clear colorless liquid

Chemical properties

2-Methoxy-3-(1-methylpropyl)pyrazine has an odor like green peas, galbanum oil or bell pepper.

Occurrence

Reported found in asparagus, carrot, celery, cucumber, lettuce, peas, bell pepper, ginger, Swiss cheese, white wine, beans, beetroot, parsnip root and pumpkin, sherry and krill.

The Uses of 2-Methoxy-3-sec-butyl pyrazine

A compound contents in musts and wines from Vitis vinifera variety Cabernet Sauvignon

Preparation

By condensation of isoleucine amide with glyoxal, followed by methylation with CH2N2.

Definition

ChEBI: 2-methoxy-3-(1-methylpropyl) pyrazine is a member of pyrazines and an aromatic ether.

Aroma threshold values

Detection: 0.001 ppb. Aroma characteristics at 1.0%: musty, green, vegetative, nutty, peppery and potato-like.

Taste threshold values

Taste characteristics at 1.0 ppm: musty, vegetative, potato, galbanum, fishy and earthy.

General Description

2-sec-Butyl-3-methoxypyrazine was identified as the main source of earthy/bell pepper (EBP) flavor in the Farmstead Cheddar cheeses.

Properties of 2-Methoxy-3-sec-butyl pyrazine

Boiling point:	50 °C1 mm Hg(lit.)
Density	1 g/mL at 25 °C
refractive index	n20/D 1.492(lit.)
FEMA	3433 \| 2-METHOXY-3-(1-METHYLPROPYL)PYRAZINE
Flash point:	171 °F
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	0.80±0.10(Predicted)
form	Liquid
color	Clear colorless
Specific Gravity	1.01
Odor	at 0.10 % in dipropylene glycol. musty green pea galbanum bell pepper
JECFA Number	791
CAS DataBase Reference	24168-70-5(CAS DataBase Reference)
NIST Chemistry Reference	Pyrazine, 2-methoxy-3-(1-methylpropyl)-(24168-70-5)
EPA Substance Registry System	Pyrazine, 2-methoxy-3-(1-methylpropyl)- (24168-70-5)

Safety information for 2-Methoxy-3-sec-butyl pyrazine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H227:Flammable liquids H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. P501:Dispose of contents/container to..…