2-Methoxy-3-methylpyrazine
- CAS NO.：2847-30-5
- Empirical Formula: C6H8N2O
- Molecular Weight: 124.14
- MDL number: MFCD00006127
- EINECS: 220-651-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-06-26 21:45:57
What is 2-Methoxy-3-methylpyrazine?
Chemical properties
clear colourless liquid
Chemical properties
2 or 5 or 6-Methoxy-3-methylpyrazine has an aroma reminiscent of hazelnut, almond and peanut. The methyl methoxy pyrazines are used as nut-like flavoring agents for foods and beverages. The 2-methoxy-3-methyl derivative is used as a coffee aroma enhancing agent.
Occurrence
Reported found in sherry and krill.
Preparation
From 2-methylpyrazine by various routes.
Definition
ChEBI: 2-Methoxy-3-methylpyrazine is a member of pyrazines and an aromatic ether.
Aroma threshold values
Detection: 3 to 7 ppb
General Description
Lowest observable adverse effect levels of 2-methoxy-3-methylpyrazine which inhibits ciliary beat frequency, oocyte pickup rate and infundibular smooth muscle contraction in the hamster oviduct has been evaluated.
Properties of 2-Methoxy-3-methylpyrazine
| Boiling point: | 48-52°C 10mm |
| Density | 1.06 g/mL at 25 °C (lit.) |
| refractive index | n |
| FEMA | 3183 | 2,5 OR 6-METHOXY-3-METHYLPYRAZINE (MIXTURE OF ISOMERS) |
| Flash point: | 132 °F |
| storage temp. | Sealed in dry,Room Temperature |
| form | clear liquid |
| pka | 1.01±0.10(Predicted) |
| color | Colorless to Light yellow |
| Odor | at 0.10 % in dipropylene glycol. nutty roasted hazelnut barly |
| JECFA Number | 788 |
| BRN | 878809 |
| CAS DataBase Reference | 2847-30-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Methoxy-3-methyl pyrazine(2847-30-5) |
| EPA Substance Registry System | Pyrazine, 2-methoxy-3-methyl- (2847-30-5) |
Safety information for 2-Methoxy-3-methylpyrazine
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-Methoxy-3-methylpyrazine
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