2-Mercaptothiazoline

Chemical properties

white to beige fine crystalline powder

The Uses of 2-Mercaptothiazoline

medicament.;medical agent; brightening agent

The Uses of 2-Mercaptothiazoline

2-Mercaptothiazoline is an antithyroid agent that strongly reduces thyroid hormone levels. 2-Mercaptothiazoline is also used as an intermediate in the preparation of pesticides and other biologically active compounds.

The Uses of 2-Mercaptothiazoline

2-Mercaptothiazoline, is used in the chain-lengthening of alkyl halides by trans-iodopropenylenation. 2-Mercaptothiazoline is an antithyroid agent that strongly reduces thyroid hormone levels. 2-Mercaptothiazoline is also used as an intermediate in the preparation of biologically active compounds. It is also used as a tool for highly selective chiral synthesis of penam- and carbapenam-type β-lactam antibiotics.

What are the applications of Application

2-Thiazoline-2-thiol is a tool for highly selective chiral syntheses of penam- and carbapenam-type β-lactam antibiotics

Purification Methods

Purify the thiol by dissolution in aqueous alkali, precipitation by addition of HCl and then recrystallisation from H2O (as needles). [IR: Flett J Chem Soc 347 1953 and Mecke et al. Chem Ber 90 975, Gabriel & Stelzner Chem Ber 28 2931 1895, Beilstein 27 III/IV 2540.]