2-MERCAPTOPYRIDINE N-OXIDE

CAS NO.：304675-78-3
Empirical Formula: C5H5NOS
Molecular Weight: 127.16
MDL number: MFCD00006196
EINECS: 679-114-3
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 01:27:02

What is 2-MERCAPTOPYRIDINE N-OXIDE?

Chemical properties

OFF-WHITE TO YELLOWISH GRANULAR CRYST. POWDER

Preparation

A solution of 60 gm (0.284) of 2-bromopyridine N-oxide hydrochloride is neutralized with 25% aqueous sodium hydroxide. In a well-ventilated hood, to this solution, heated with stirring on a steam bath, is added dropwise over a 1-hr period a solution of 32 gm (0.57 mole) of sodium hydrogen sulfide in 150 ml of water. After the addition has been completed, heating is continued for 0.5 hr. The reaction mixture is cooled, filtered, and acidified with 6 Ν hydrochloric acid to afford 24 gm (67%), m.p. 65-68°C. Upon recrystallization from aqueous ethanol, the melting point is raised to 68-70°C.
Similar results were obtained when an equivalent quantity of sodium sulfide was substituted for sodium hydrogen sulfide.
Preparation of N-Hydroxy-2-pyridinethione

Properties of 2-MERCAPTOPYRIDINE N-OXIDE

Melting point:	70-72 °C
Boiling point:	109 °C
Density	1.22
form	Granular Crystalline Powder
color	Off-white to yellow
Merck	14,7994

Safety information for 2-MERCAPTOPYRIDINE N-OXIDE

Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.