2-Linoleoyl-rac-glycerol

Synonym(s):β-Monolinolein;(9Z,12Z)-9,12-Octadecadienoic acid 2-hydroxy-1-(hydroxymethyl)ethyl ester;2-Monolinolein;2-Monolinoleoylglycerol

CAS NO.：3443-82-1
Empirical Formula: C21H38O4
Molecular Weight: 354.52
MDL number: MFCD05863969
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:48:07

What is 2-Linoleoyl-rac-glycerol?

Chemical properties

Colourless Oil

The Uses of 2-Linoleoyl-rac-glycerol

A fatty acid

The Uses of 2-Linoleoyl-rac-glycerol

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG. Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.

The Uses of 2-Linoleoyl-rac-glycerol

A fatty acid monoglycerides in vegetable oils with medium unsaturation.

What are the applications of Application

2-Linoleoyl glycerol is an endocannabinoid which potentiates the action of other endocannabinoids

What are the applications of Application

2-Linoleoyl-rac-glycerol is A fatty acid monoglycerides in vegetable oils with medium unsaturation

Definition

ChEBI: A 2-monoglyceride where linoleoyl forms the 2-acyl group.

Properties of 2-Linoleoyl-rac-glycerol

Melting point:	9°C
Boiling point:	485.0±40.0 °C(Predicted)
Density	0.981±0.06 g/cm3(Predicted)
Flash point:	2℃
storage temp.	-20°C
solubility	Chloroform (Slightly), DMF (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form	Oil
pka	13.54±0.10(Predicted)
color	Colourless to Pale Yellow
BRN	1715064
Stability:	Temperature Sensitive
CAS DataBase Reference	3443-82-1

Safety information for 2-Linoleoyl-rac-glycerol

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.