2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL

CAS NO.：2814-20-2
Empirical Formula: C8H12N2O
Molecular Weight: 152.19
MDL number: MFCD00044811
EINECS: 220-561-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL?

Chemical properties

BEIGE NEEDLES

The Uses of 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL

2-Isopropyl-6-methyl-4-pyrimidone, is an intermediate used for the synthesis of various benzophenone derivatives, having antifungal and antibacterial activities. It can also be used for the synthesis of Diazinon (D416880), and Diazoxon (D416890), the organophosphate insecticides.

Definition

ChEBI: 2-isopropyl-6-methyl-4-pyrimidinone is a pyrimidone that is pyrimidin-4(1H)-one substituted by a methyl group at position 6 and an isopropyl group at position 2. It is a metabolite of diazinon. It has a role as a marine xenobiotic metabolite. It is a tautomer of a 2-isopropyl-6-methylpyrimidin-4-ol.

General Description

2-Isopropyl-6-methyl-4-pyrimidinol is a pyrimidine compound. It is reported as an major metabolite of pesticide diazinon., It has been identified as urinary metabolite in the general population exposed to organophosphorus compounds (insecticides, flame retardants and plasticizers) and moth repellents used in Japanese households. Photocatalytic oxidation of 2-isopropyl-6-methyl-4-pyrimidinol has been reported.

Properties of 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL

Melting point:	172-175 °C(lit.)
Boiling point:	274.67°C (rough estimate)
Density	1.0996 (rough estimate)
refractive index	1.4940 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	9.74±0.50(Predicted)
color	White to Off-White
CAS DataBase Reference	2814-20-2(CAS DataBase Reference)
EPA Substance Registry System	6-Methyl-2-(1-methylethyl)-4(1H)-pyrimidinone (2814-20-2)

Safety information for 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.