2-HYDROXYSACLOFEN
Synonym(s):3-Amino-2-(4-chlorophenyl)-2-hydroxypropanesulfonic acid
- CAS NO.：117354-64-0
- Empirical Formula: C9H12ClNO4S
- Molecular Weight: 265.71
- MDL number: MFCD00069282
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is 2-HYDROXYSACLOFEN?
The Uses of 2-HYDROXYSACLOFEN
2-Hydroxysaclofen is a GABA-B receptor antagonist in the ventral tegmental area and may play a role in the mechanisms of cocaine usage. Affects specific acute nicotine responses in mice, abolishing hypolocomotion and increasing antinociception.
What are the applications of Application
2-Hydroxysaclofen is a selective GABAB antagonist
Definition
ChEBI: 3-amino-2-(4-chlorophenyl)-2-hydroxy-1-propanesulfonic acid is an organochlorine compound.
Biological Activity
Selective antagonist at GABA B receptors.
Storage
Store at RT
Properties of 2-HYDROXYSACLOFEN
| Melting point: | 267-269 °C |
| RTECS | DA0359200 |
| storage temp. | 2-8°C |
| solubility | H2O: 1 mg/mL |
| form | solid |
| color | white |
| Water Solubility | Soluble in water at 1mg/ml. Also soluble in DMSO, 0.1M HCl and methanol |
Safety information for 2-HYDROXYSACLOFEN
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-HYDROXYSACLOFEN
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