2-HYDROXYCARBAZOLE
Synonym(s):2-Carbazolol
- CAS NO.：86-79-3
- Empirical Formula: C12H9NO
- Molecular Weight: 183.21
- MDL number: MFCD00004962
- EINECS: 201-699-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:09:18
What is 2-HYDROXYCARBAZOLE?
Chemical properties
beige to light brown crystalline powder
The Uses of 2-HYDROXYCARBAZOLE
Carbazol has been found possible to distinguish between heparin, heparin derivatives, and other polyuronides of connective tissue. A new modification of the carbazole analysis is useful for determination of d-mannuronic acid in heteropolysaccharides. 2-Hydroxycarbazole was used in the synthesis of isochromene fused carbazol, (4aS,13bR)-2,5,5-trimethyl-3,4,4a,5,8,13b-hexahydroisochromeno[3,4-b]carbazole.
General Description
2-Hydroxycarbazole is a compound structurally related to the Ca2+-mobilizing marine toxin, 9-methyl-7-bromoeudistomin. Room temperature electronic absorption and fluorescence spectra of 2-hydroxycarbazole has been studied in concentrated aqueous potassium hydroxide solutions. It undergoes chemoselective N-alkylation using NaH as a base in a THF-DMF solvent system.
Properties of 2-HYDROXYCARBAZOLE
| Melting point: | 270-273 °C (lit.) |
| Boiling point: | 316.88°C (rough estimate) |
| Density | 1.1261 (rough estimate) |
| refractive index | 1.5880 (estimate) |
| pka | 10.05±0.30(Predicted) |
| color | Grey |
| BRN | 135859 |
| CAS DataBase Reference | 86-79-3(CAS DataBase Reference) |
Safety information for 2-HYDROXYCARBAZOLE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-HYDROXYCARBAZOLE
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