2-HYDROXY-1-NAPHTHOIC ACID
- CAS NO.：2283-08-1
- Empirical Formula: C11H8O3
- Molecular Weight: 188.18
- MDL number: MFCD00004009
- EINECS: 218-919-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:59
What is 2-HYDROXY-1-NAPHTHOIC ACID?
Chemical properties
2-Hydroxy-1-naphthoic acid [2283-08-1], C11H8O3, Mr 188.17, has a mp of 156 – 157℃ (decomp. to 2-naphthol and CO2). The monosodium salt is unstable in hot aqueous solution. 2- Hydroxy-1-naphthoic acid is decarboxylated by nitrous acid, forming 1-nitroso-2-naphthol, and by diazo salts, forming a 1-azo-2-naphthol. An ethanolic solution of 2-hydroxy-1-naphthoic acid gives a dark blue color with iron(III) chloride. Chlorosulfonic acid at 30℃ gives the 6-sulfonyl chloride derivative.
The Uses of 2-HYDROXY-1-NAPHTHOIC ACID
?2-Hydroxy-1-naphthoic acid is an intermediate of minor importance in the synthesis of azo dyes.
Production Methods
Treatment of the dried sodium or potassium salt of 2-naphthol with carbon dioxide at 120 C under pressure gives an 80 % yield of product after careful work-up. Solvents such as toluene, tetralin, or diphenyl oxide are patented alternatives.
Properties of 2-HYDROXY-1-NAPHTHOIC ACID
| Melting point: | 167 °C (dec.) (lit.) |
| Boiling point: | 283.17°C (rough estimate) |
| Density | 1.2100 (rough estimate) |
| refractive index | 1.6400 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | pK1:3.29;pK2:9.68 (20°C) |
| form | powder to crystal |
| color | White to Light red to Green |
| BRN | 975575 |
| CAS DataBase Reference | 2283-08-1(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Naphthalenecarboxylic acid, 2-hydroxy- (2283-08-1) |
Safety information for 2-HYDROXY-1-NAPHTHOIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-HYDROXY-1-NAPHTHOIC ACID
2-HYDROXY-1-NAPHTHOIC ACID manufacturer
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
You may like
-
2-Hydroxy-1-naphthoic Acid CAS 2283-08-1View Details
2283-08-1 -
2-Hydroxy-1-naphthoic acid CAS 2283-08-1View Details
2283-08-1 -
2-Hydroxy-1-Naphthoic AcidView Details
2283-08-1 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
10442-39-4 TETRABUTYLAMMONIUM CYANIDE 98+View Details
10442-39-4 -
68208-21-9 98+View Details
68208-21-9 -
3-Amino-3-(3-fluorophenyl)propanoic acid 98+View Details
117391-51-2 -
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4 98+View Details
68208-18-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.