2-Fluorobenzoyl chloride
- CAS NO.：393-52-2
- Empirical Formula: C7H4ClFO
- Molecular Weight: 158.56
- MDL number: MFCD00000656
- EINECS: 206-887-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:06
What is 2-Fluorobenzoyl chloride?
Chemical properties
clear colorless to faintly colored liquid
The Uses of 2-Fluorobenzoyl chloride
2-Fluorobenzoyl Chloride (cas# 393-52-2) is a compound useful in organic synthesis.
The Uses of 2-Fluorobenzoyl chloride
2-Fluorobenzoyl chloride has been used in the preparation of 3-(N-Hydroxycarbamimidoyl)-benzoic acid methyl ester. It has been used to develop an hollow-fiber liquid phase microextraction with in situ derivatization method coupled with HPLC-UV for the determination of metformin hydrochloride in biological fluids.
General Description
Colorless liquid.
Air & Water Reactions
Decomposes in water to form HCl with generation of heat
Reactivity Profile
2-Fluorobenzoyl chloride is sensitive to moisture. Incompatible with water, alcohol, bases (including amines) and with oxidizing agents . May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Fire Hazard
2-Fluorobenzoyl chloride is combustible.
Properties of 2-Fluorobenzoyl chloride
| Melting point: | 4 °C (lit.) |
| Boiling point: | 90-92 °C/15 mmHg (lit.) |
| Density | 1.328 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 180 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly) |
| form | Liquid |
| Specific Gravity | 1.328 |
| color | Clear colorless to faintly colored |
| Water Solubility | Decomposition |
| Sensitive | Lachrymatory |
| BRN | 636864 |
| CAS DataBase Reference | 393-52-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoyl chloride, 2-fluoro-(393-52-2) |
| EPA Substance Registry System | o-Fluorobenzoyl chloride (393-52-2) |
Safety information for 2-Fluorobenzoyl chloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Fluorobenzoyl chloride
New Products
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