Thiocarbohydrazide

Synonym(s):Thiocarbonyldihydrazide

CAS NO.：2231-57-4
Empirical Formula: CH6N4S
Molecular Weight: 106.15
MDL number: MFCD00007616
EINECS: 218-769-8
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-24 18:13:48

What is Thiocarbohydrazide?

Chemical properties

white to grey-beige crystalline powder

The Uses of Thiocarbohydrazide

Thiocarbohydrazide is used in electron microscopy to produce electron-opaque deposits for ultra structural analysis. It is used in the synthesis of oxazine grass ketones.

Definition

ChEBI: Thiocarbohydrazide is a thiocarbonyl compound.

General Description

Crystalline needles and plates. Used in electron microscopy to produce electron-opaque deposits for ultra structural analysis.

Reactivity Profile

Thiocarbohydrazide is a thioamide, which may behave as a weak base and therefore will react with acids forming salts with production of heat. Thiocarbohydrazide may react with acids and reducing agents to form toxic hydrogen sulfide gas. This may be vigorous depending on the nature of the reducing agent. Organic amides/imides react with azo and diazo compounds to generate toxic gases. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Health Hazard

High oral toxicity.

Fire Hazard

When heated to decomposition Thiocarbohydrazide emits very toxic fumes of nitrogen oxides and sulfur oxides.

Properties of Thiocarbohydrazide

Melting point:	171-174 °C (dec.)(lit.)
Boiling point:	230.1±23.0 °C(Predicted)
Density	1.273 (estimate)
refractive index	1.5605 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Very slightly soluble (0.5g/100g, 25°C). Insoluble in ether.
pka	10.58±0.70(Predicted)
form	Crystalline Powder
color	White to gray-beige
Sensitive	Light Sensitive
BRN	506657
CAS DataBase Reference	2231-57-4(CAS DataBase Reference)
NIST Chemistry Reference	Carbonothioic dihydrazide(2231-57-4)
EPA Substance Registry System	Thiocarbazide (2231-57-4)

Safety information for Thiocarbohydrazide

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H311:Acute toxicity,dermal
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection.