2-Fluorobenzenesulfonyl chloride

CAS NO.：2905-21-7
Empirical Formula: C6H4ClFO2S
Molecular Weight: 194.61
MDL number: MFCD00042285
EINECS: 628-227-6
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is 2-Fluorobenzenesulfonyl chloride?

Chemical properties

clear colorless to yellow liquid

The Uses of 2-Fluorobenzenesulfonyl chloride

2-Fluorobenzenesulfonyl chloride may be used in the preparation of the following furan derivatives:

2-(2-fluorophenyl)benzofuran
2-butyl-5-(2-fluorophenyl)furan
2-(2-fluorophenyl)-3,6-dimethyl-4,5,6,7-tetrahydrobenzofuran

It may also be used to prepare:

2-fluorobenzenesulfonamide
methyl 2-{[(2-fluorophenyl)sulfonyl]amino}-5,6,7,8-tetrahydro-1-naphthalenecarboxylate
potassium fluorobenzene-2-sulfonate
1-(2-bromobenzyl)-2-(2-fluorophenyl)pyrrole

General Description

2-Fluorobenzenesulfonyl chloride, also known as o-fluorobenzenesulfonyl chloride, is a flurinated arylsulfonyl chloride. It can be prepared from o-benzenedisulfonyl fluoride.

Properties of 2-Fluorobenzenesulfonyl chloride

Melting point:	27-30 °C (lit.)
Boiling point:	246-247 °C (lit.)
Density	1.47 g/mL at 25 °C (lit.)
refractive index	n20/D 1.537(lit.)
Flash point:	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Liquid
color	Clear colorless
Specific Gravity	1.470
Sensitive	Moisture Sensitive
BRN	2093979
CAS DataBase Reference	2905-21-7(CAS DataBase Reference)

Safety information for 2-Fluorobenzenesulfonyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.