2-fluoro Palmitic Acid methyl ester

Description

2-fluoro Palmitic acid methyl ester is a monofluorinated form of palmitic acid methyl ester . It is an intermediate in the synthesis of 2-iodoaldehydes, monofluorinated fatty acids, and polyfluoro ketones.^1,2,3

References

1. Panneels, V., Van den Bergen, H., Jacoby, C., et al. Inhibition of H₂O₂ production by iodoaldehydes in cultured dog thyroid cells Mol. Cell Endocrinol. 102(1-2),167-176(1994).
2. Delgado, A., Ruiz, M.A., Camps, F., et al. Synthesis of potential inhibitors of the biosynthesis of the sex pheromone of Spodoptera littoralis. Part I: Monofluorinated fatty acids Chem. Phys. Lipids 59(2),127-135(1991).
3. Baskakis, C., Magrioti, V., Cotton, N., et al. Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A₂ enzymes J. Med. Chem. 51(24),8027-8037(2008).