2-Fluoro-3-methylpyridine

Synonym(s):2-Fluoro-3-picoline

CAS NO.：2369-18-8
Empirical Formula: C6H6FN
Molecular Weight: 111.12
MDL number: MFCD00041223
EINECS: 624-901-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-25 17:15:13

What is 2-Fluoro-3-methylpyridine?

Chemical properties

clear colorless to light yellow liquid

The Uses of 2-Fluoro-3-methylpyridine

2-Fluoro-3-methylpyridine may be used in the preparation of:

2-phenyl-3-methylpyridine
2-(4-chlorophenyl)-3-methylpyridine
2-(4-fluorophenyl)-3-methylpyridine
2-fluoronicotinic acid

General Description

2-Fluoro-3-methylpyridine, also known as 2-fluoro-3-picoline, can be prepared by reacting 2-amino-3-methylpyridine and 40% fluoroboric acid.2 The signs of the long range coupling constants of 2-fluoro-3-methylpyridine have been obtained by double and triple resonance techniques.

Properties of 2-Fluoro-3-methylpyridine

Boiling point:	154-155 °C (lit.)
Density	1.098 g/mL at 25 °C (lit.)
refractive index	n20/D 1.476(lit.)
Flash point:	119 °F
storage temp.	Inert atmosphere,2-8°C
form	clear liquid
pka	-0.14±0.10(Predicted)
Specific Gravity	1.098
color	Colorless to Light orange to Yellow
BRN	1877
CAS DataBase Reference	2369-18-8(CAS DataBase Reference)

Safety information for 2-Fluoro-3-methylpyridine

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.