2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE
Synonym(s):(E)-2-[(1-Benzylpiperidin-4-yl)methylene]-5,6-dimethoxyindan-1-one
- CAS NO.：145546-80-1
- Empirical Formula: C24H27NO3
- Molecular Weight: 377.48
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:07:08
![2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE Structural](https://img.chemicalbook.in/CAS/GIF/145546-80-1.gif)
What is 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE?
The Uses of 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE
(2E)-Dehydrodonepezil (Donepezil USP Related Compound A) is a derivative of Donepezil (D531750), a nootropic. An inhibitor of acetylcholinesterase.
Properties of 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE
| Boiling point: | 542.8±50.0 °C(Predicted) |
| Density | 1.209±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 8.17±0.10(Predicted) |
| color | Pale Yellow to Light Yellow |
| CAS DataBase Reference | 145546-80-1 |
Safety information for 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H300:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. P501:Dispose of contents/container to..… |
Computed Descriptors for 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE
2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE manufacturer
GLP Pharma Standards
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product: Donepezil EP Impurity F/ Donepezil USP Related Compound A / (E)-Dehydro Donepezil 145546-80-1 NLT 95%
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