2-(DIMETHYLSILYL)PYRIDINE
Synonym(s):Dimethyl(2-pyridyl)silane
- CAS NO.：21032-48-4
- Empirical Formula: C7H11NSi
- Molecular Weight: 137.25
- MDL number: MFCD06797091
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:14:21
What is 2-(DIMETHYLSILYL)PYRIDINE?
Physical properties
bp 68–72 °C/20 mm Hg.
The Uses of 2-(DIMETHYLSILYL)PYRIDINE
2-Pyridyldimethylsilane is reagent used for metal-catalyzed hydrosilylation of alkynes and alkenes.Presumably because of the presence of catalyst-directing pyridyl group on silicon, 2- pyridyldimethylsilane exhibits greater reactivity in Rh-catalyzed hydrosilylation of alkenes than those of other related hydrosilanes. Moreover, the presence of the basic pyridyl group enables easy product separation and facile catalyst recovery through simple acid/base extraction.
The Uses of 2-(DIMETHYLSILYL)PYRIDINE
A useful scaffold for a number of reactions including hydrosilylation, cross-coupling, and olefination.
Preparation
2-Pyridyldimethylsilane can be prepared by reaction of 2-pyridyllithium with chlorodimethylsilane in dry Et2O at ?78°Cunder argon.
Properties of 2-(DIMETHYLSILYL)PYRIDINE
| Boiling point: | 175-178 °C(Press: 758 Torr) |
| Density | 0.92 |
| refractive index | n20/D 1.499 |
| Flash point: | 41 °C |
| storage temp. | 2-8°C |
| solubility | soluble in most common organic solvents. |
| pka | 5.40±0.12(Predicted) |
| CAS DataBase Reference | 21032-48-4 |
Safety information for 2-(DIMETHYLSILYL)PYRIDINE
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-(DIMETHYLSILYL)PYRIDINE
New Products
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![2,2'-[METHYLENEBIS(DIMETHYLSILYLENE)]BISPYRIDINE](https://img.chemicalbook.in/CAS/GIF/243468-48-6.gif)
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