2'-Deoxycytidine-5'-monophosphoric acid

Chemical properties

Crystalline

The Uses of 2'-Deoxycytidine-5'-monophosphoric acid

A phosphorylated metabolite of the deoxyribonucleoside 2’Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferatio n.

The Uses of 2'-Deoxycytidine-5'-monophosphoric acid

2'-Deoxycytidine-5'-monophosphate is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation to dCTP supports DNA and RNA biosynthesis.

What are the applications of Application

2′-Deoxycytidine 5′-monophosphate is a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase

Definition

ChEBI: Dianion of 2'-deoxycytidine 5'-monophosphate arising from deprotonation of both OH groups of the phosphate.

General Description

2′-Deoxycytidine 5′-monophosphate is a deoxynucleotide building block via which DNA is made. It consists of a 2′-deoxy-β-D-ribofuranose, linked through an N-β-D-glycosidic linkage to a heterocycle nitrogen cytosine. It is phosphorylated at carbon C-5′.

Purification Methods

Recrystallise the acid from H2O or aqueous EtOH and dry it in a vacuum. [Volkin et al. J Am Chem Soc 73 1533 1951, UV: Fox et al. J Am Chem Soc 75 4315 1953, IR: Michelson & Todd J Chem Soc 3438 1954, Beilstein 25 IV 3664.]