Deoxycytidine triphosphate
- CAS NO.：2056-98-6
- Empirical Formula: C9H16N3O13P3
- Molecular Weight: 467.16
- MDL number: MFCD00135938
- EINECS: 218-153-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-27 08:46:37
What is Deoxycytidine triphosphate?
The Uses of Deoxycytidine triphosphate
Isotope labelled 2’-Deoxycytidine 5’-Triphosphate Triethylamine, a labelled metabolite of 2’-Deoxycytidine, a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction.
Definition
ChEBI: DCTP is a 2'-deoxycytidine phosphate having cytosine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a 2'-deoxycytidine phosphate and a pyrimidine 2'-deoxyribonucleoside 5'-triphosphate. It is a conjugate acid of a dCTP(3-).
Biological Activity
Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used in DNA synthesis. Deoxycytidine triphosphate can be used in real-time PCR, cDNA synthesis and DNA sequencing research.
in vitro
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.
Properties of Deoxycytidine triphosphate
| Boiling point: | 811.5±75.0 °C(Predicted) |
| Density | 2.38±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.80±0.50(Predicted) |
| form | Stabilized Aqueous Solution |
| color | White to off-white |
| Water Solubility | Water : ≥ 35 mg/mL (74.92 mM) |
Safety information for Deoxycytidine triphosphate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Deoxycytidine triphosphate
New Products
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