2-Cyano-5-methoxypyridine
- CAS NO.：89809-63-2
- Empirical Formula: C7H6N2O
- Molecular Weight: 134.14
- MDL number: MFCD08543467
- EINECS: 200-589-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-16 09:52:51
What is 2-Cyano-5-methoxypyridine?
What are the applications of Application
5-Methoxypyridine-2-carbonitrile is a building block for research
Synthesis
To a mixture of 2-cyano-5-hydroxy pyridine (200 mg, 1.66 mmol), DMF (10 mL) and K2CO3 (253 mg, 1.83 mmol), was added MeI (354 mg, 2.49 mmol) at room temperature and the reaction mix was stirred for 24 h at room temperature. The reaction mix was poured into water and extracted with ethyl acetate. The organic layer was separated, washed with water, dried and concentrated to give 2-Cyano-5-methoxypyridine (175 mg, 78% yield).
Properties of 2-Cyano-5-methoxypyridine
| Boiling point: | 292.1±20.0 °C(Predicted) |
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | -4.06±0.10(Predicted) |
Safety information for 2-Cyano-5-methoxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2-Cyano-5-methoxypyridine
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